PCS is a persistence or recurrence of Upper abdominal pain and dyspepsia after cholecystectomy and encompass biliary or non-biliary disorders possibly related or unrelated to cholecystectomy. The common biliary causes is usually remnant of gallbladder or cystic duct stump containing small stone or retained stone in the common bile duct. The uncommon biliary cause include inflammatory biliary stricture, bile leak/ bile duct injury or Sphincter of Oddi dysfunction. The non-biliary cause usually range from Peptic ulcer disease to functional Bowel disorder such as IBS or Musculoskeletal pain.
PCS usually require investigation with MRCP or CT scan for biliary cause, OGD for peptic ulcer and very rarely ERCP/Sphincter of Oddi Manometry for SOD dysfunction. Treatment is based on the cause.
Post-cholecystectomy syndrome: spectrum of biliary findings at magnetic resonance cholangiopancreatography. The British Journal of Radiology, 83 (2010), 351–361